Nutrim and Cholesterol
Oat-derived ß-Glucan Significantly Improves HDLC and Diminishes LDLC and Non-HDL Cholesterol in Overweight Individuals with Mild Hypercholestrolemia
Summary: 38 overweight men with high cholesterol were split equally placed on an AHA step II diet with either 6g of fiber from wheat bread or 6g ß-glucan from Nutrim® baked into bread. They were also instructed to walk for 60 minutes a day. At the end of 8 weeks the subjects had blood draws that were then compared to their initial blood work. The Nutrim® group saw significant improvement in lipid profile and body weight without any adverse effects.
Oat Beta Glucan and Cholesterol
Oat ß-Glucan increases bile acid excretion and a fiber-rich barley fraction increases cholesterol execretion in ileostomy subjects
Quote from Study
Oat ß-glucan mediates an increase in bile acid secretion, which most probably explains the effect of oat fiber in lowering cholesterol
Summary: 10 ileostomy patients were fed 4 diets, each for 2 days. The 4 diets included 4 different types of bread: oat bran, oat bran with ß-glucanase (an enzyme that breaks down ß-glucans), barley, and wheat. Feeding oat bran bread resulted in a 53% higher bile acid secretion compared to oat bran bread with ß-glucanase. Oat bran bread also resulted in significantly more excretion of bile acids compared with barley and wheat breads.
Effects of oat gum on the physical properties of the gastrointestinal contents and on the uptake of D-galactose and cholesterol by rat small intestine in vitro
Quote from Study
…increased viscosity of the contents of the small intestine may contribute to the low glycemic index and hypocholesterolaemic effects of oats in man
Summary: Wister rats were fed 3 meals of either a control diet, a diet containing oat gum (ß-glucan), or finely ground rolled oats. The oat meals increased intestinal viscosity and wet to dry ratio of digestive tract contents. Cholesterol uptake and sugar was inhibited by oat gum.
ß-Glucan incorporated into a fruit drink effectively lowers serum LDL cholesterol concentrations
Quote from Study
A reduced cholesterol absorption contributes to the cholesterol lowering effect of ß-glucans without affecting plasma concentrations of lipid soluble antioxidants.
Summary: 22 participants consumed 5g of rice starch and 25 participants consumed 5 g of ß-glucans from oats for 3 weeks. The ß-glucan group lowered total and LDL cholesterol. Cholesterol absorption was reduced without reducing absorption of fat soluble antioxidants.
Cholesterol lowering benefits of oat-containing cereal in Hispanic Americans
Quote from Study
Consumption of oat cereal was associated with a reduction in plasma levels of both total cholesterol and LDL-c.
Summary: 152 men and women were randomly assigned to eat 3g ß- glucans from oat cereal or corn cereal. The ß-glucan group significantly lowered total and LDL cholesterol while corn slightly raised cholesterol.
Effects of oat bran enriched diet on the atherogenic lipid profile in patients with an increased coronary heart disease risk. A controlled randomized lifestyle intervention study
Quote from Study
…oat bran, within a practical range of intake significantly reduces total cholesterol, low-density lipoprotein cholesterol, and apolipoprotein B… independant of covariables such as physical activity or caloric and fat restriction in the diet.
Summary: 99 patients received a fat modified diet with caloric restriction, exercise, and health education along with 35-50g of oat bran per day, while 136 men received the same diet and lifestyle program without oat bran. 53 men served as controls. A significant reduction was seen in the oat bran group for total (-67.7 mg/dl) and LDL cholesterol(-56.3mg/dl), as well as a reduction in apolipoprotein(-42.4mg/dl).
Oat ß-glucan reduces blood cholesterol concentrations in hypercholesterolemic subjects
Quote from Study
The main component of the soluble fiber of oats, ß-glucan, significantly reduced the total and LDL cholesterol levels of hypercholesterolemic adults…
Summary: A crossover study was carried out with 19 Men and women who were fed either 2.9g ß-glucan twice per day or a placebo for 4 weeks. The placebo made no significant changes in cholesterol while the ß-glucan reduced total and LDL cholesterol.
Concentrated oat ß-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial
Quote from Study
Thus, a practical dose of β-glucan can significantly lower serum lipids in a high-risk population and may improve colon health.
Summary: 75 men and women were randomly assigned to either 6g/day of oat ß-glucan or 6 grams/day of dextrose for 6 weeks. The ß-glucan group saw significant decreases in total and LDL cholesterol compared with the placebo group.